The ability to induce apoptosis for inhibiting viral replication is reduced in airway epithelial cells of asthma patients infected with rhinoviruses (52) in general, rhinovirus infection causes the production of type 1 interferons (IFN), IFN-α and IFN-β, and type 3 interferon, IFN-λ, in airway epithelial cells. This evidence concerns the gene IFNA1 and asthma.