However, in the case of HFCFD-induced MASLD model, the YBX1-KOhep mice exhibited lower body weight, liver size, LW/BW, liver TG content, ALT, plasma lipid levels, and lesser accumulation of hepatic lipids than the LOXP mice (Figure 2B-G and S2B-F). Here, GPT is linked to metabolic dysfunction-associated steatotic liver disease.