We established a xenograft tumor model in nude mice using BRD7-interfered CNE2 cells and treated the tumor-bearing mice with LY-294002 and HO-3867, showing that downregulation of BRD7 expression promoted tumor growth in vivo, while treatment with LY-294002 and HO-3867 reversed the promoting effect of BRD7 downregulation on tumor growth (Figure S3D). Here, BRD7 is linked to neoplasm.