Western blot was performed to identify the four genes expression in LCOR overexpressed ccRCC cell lines and results indicated that only PLCL1 was elevated in both A498 and CAKI cells, the ALOX5 was decreased in A498 but increased in CAKI cells, the CYP2J2 and ACOT11 remained unchanged (Fig. 4C). The gene discussed is CYP2J2; the disease is nonpapillary renal cell carcinoma.