TGFB1 and cancer: Other analyses provided concordance with the impact of FAT1 on the immune landscape of breast cancer where among different cancer types, FAT1 expression recorded notable associations with key immunomodulatory molecules such as TGF-β and TGF-βR1, together with a range of cytokines including CX3CL1 and other CXCL members, as well as influencing key types of tumor-infiltrating immune cells.