Severe anemia (hemoglobin 68 g/L) with retikulocytosis and critical thrombocytopenia (platelets 12109/L), elevated lactate dehydrogenase (1.280 U/L) and total bilirubin (2.3 mg/dL), and decreased haptoglobin level ( < 0.06 g/L), presence of 3% schistocytes. The gene discussed is HP; the disease is anemia.