Haemolytic anaemia with a haemoglobin of 63 g/L, platelets < 10 × 1012/L, bilirubin 68 μmol/L, lactate dehydrogenase (LDH) 626 μ/L, haptoglobin < 0·10 g/L, and the occasional red cell fragment noted on blood film, ADAMTS13 activity testing showing a level of < 1% and ADAMTS13 IgG of 72 μ/mL. This evidence concerns the gene ADAMTS13 and non-autoimmune hemolytic anemia.