Host infection and thus the life cycle of SARS-CoV-2 begins with the Spike (S) protein, a type I membrane glycoprotein embedded in the envelope of the virus with the most variable sequences among the coronavirus genomes (Woo et al., 2010), which binds the receptor angiotensin-converting enzyme 2 (ACE2) on the target cell. This evidence concerns the gene ACE2 and infection.