A 73-year-old male patient (190 cm tall and weighing 77 kg) with Child-Pugh C cirrhosis (score 10, HE grade I, massive ascites, total bilirubin 1.4 mg/dL, albumin 2.4 g/dL, prothrombin time (PT) activity 47%) presented with a 5-cm necrotic umbilical hernia. The gene discussed is F2; the disease is Cirrhosis.