Previous studies have shown that USP7, USP10, and USP24 can stabilize p53 expression and inhibit cancer formation.78, 79, 80 However, some studies have shown that USP2 stabilizes the expression of p53 through deubiquitination, and that there is a potential role for the p53 signaling pathway to participate in the inhibition of apoptosis and to promote the growth of breast cancer cells.81 Here, USP7 is linked to breast cancer.