Phospholipase A2 group IVA (PLA2G4A), or cPLA2α, is known to modulate TGF‐β‐induced EMT in epithelial HCC cells by activating the PI3K/Akt pathway and inhibiting the TGF‐β/Smad signaling [46]. This evidence concerns the gene AKT1 and hepatocellular carcinoma.