On a mechanistic level, we showed that miR-1297 exerts its role by directly targeting EphA2 (Figure 1d-f, and 3e-g, and 4d-h) that, consistently, is differently expressed in the progression from NME towards FEA and DCIS (Figure 2f, g). The gene discussed is EPHA2; the disease is ductal breast carcinoma in situ.