Network SMR applied to cis-DNA methylation quantitative trait loci (mQTLs) data revealed pleiotropic association of some novel DNA methylation sites and genes with AD (e.g., cg05656486 (NDUFS2), cg13210467 (STAG3), and cg03887787 (FIBP)) [40]. The gene discussed is FIBP; the disease is Alzheimer disease.