Moreover, we could validate the enrichment of the EMT (fourfold, P = 1.7e-05), as well as the KRAS signaling (down) (fourfold, P = 4e-04) and coagulation (fourfold, P = 0.003) pathways using the upregulated DEGs of the CPTAC-HNSCC cohort. Here, KRAS is linked to head and neck squamous cell carcinoma.