ASCL1 and small cell lung carcinoma: Therefore, although the precise mechanism underlying co-expressed ASCL1-mediated cell death in SCLC-N cells remains to be elucidated (Fig. 8), emerging technologies such as nanomedicine43 and RNA therapeutics44 offer the potential to induce ASCL1 co-expression selectively in SCLC-N cells, presenting a more promising therapeutic strategy compared to the induction of NEUROD1 co-expression selectively in SCLC-A cells.