What is more, the dual-luciferase analysis demonstrated a significant decrease regarding transcriptional activity of CTNNB1 promoter containing YBX1-binding site following knockdown of LINC02418 in CRC cells, while LINC02418 overexpression resulted in the opposite effect (Fig. 5L-M and Figure S5A-B). This evidence concerns the gene CTNNB1 and colorectal carcinoma.