To begin with, we analyzed the highly expressed lncRNAs (logFC > 1, p < 0.05 and adj p < 0.05) in CRC tissues utilizing the GSE102340, GSE83889 and GSE81558 databases, and the Venn diagram indicated a significant upregulation of LINC02418 in CRC tissues compared to normal tissues (Fig. 1A), which was also evidenced by analyses of TCGA COADREAD, GSE87211 and GSE106582 databases (Fig. 1B–D). The gene discussed is LINC02418; the disease is colorectal carcinoma.