SRF and aneurysm: Despite this, genetic SRF depletion protected from hypertensive aortopathy prodromal to true aneurysm formation, and our proteomics experiment suggested that this was due to YAP/TAZ-driven compensatory increases of lysyl oxidase (Lox), serine protease inhibitors (Serpine1 and Serpine2), and Ctgf (Ccn2).