PLOD1 and anovulation: Thepituitary gland secretes an irregularly high amount of luteinizing hormone (LH) intothe bloodstream, disrupting a female’s normal menstrual cycle and eventuallycreating an imbalance between progesterone, estrogen, Follicle Stimulating Hormone(FSH), and (LH), which leads anovulation (Khanageet al., 2019).