Hyperandrogenism, a biochemical hallmark of PCOS, is an elevatedlevel of androgens marked in females primarily responsible for PCOS, which includescutaneous indicators such as male pattern baldness, alopecia, and hirsutism, whichresults in disturbances in GnRH pulses, giving rise to an increased level of LH/FSHratio (Goswami et al.,2012). This evidence concerns the gene PLOD1 and polycystic ovary syndrome.