However, although reported in a US population of Dobermanns, we did not find an association between the TTN SNP and DCM in our cohort of dogs, and a GWAS performed in a large European Dobermann cohort also did not find association between loci on chromosome 14 (PDK4) or chromosome 36 (TTN) [11]. Here, PDK4 is linked to familial dilated cardiomyopathy.