RNF207 and familial dilated cardiomyopathy: There was a significant difference in the allele frequencies of the RNF207 variant between DCM cases and controls (OR 2.4 (95% CI 1.07 – 5.15), p =  0.03) and genotype frequencies for RNF207, with a homozygous genotype found almost exclusively in DCM dogs (p =  0.034).