The evaluation of the logFC of the mmp‐2 gene and its isoforms (mmp‐2‐1, 3A, and 3B) was conducted in cancer cell lines and biopsies of osteosarcoma tumors from the PRJNA698672 and PRJNA518013 projects of the ENA‐EMBL. This evidence concerns the gene MMP2 and osteosarcoma.