IL10 and early-onset autosomal dominant Alzheimer disease: Another way that Tregs can act to modulate neuroinflammation is by producing immunosuppressive cytokines, such as interleukin 10 (IL-10), interleukin 35 (IL-35) and transforming growth factor beta.104 Cytokines play an important role in regulating immune responses and therefore can modulate neuroinflammation in Alzheimer’s disease.