Then, assessing the utility of Parkin levels to discriminate between clinically defined idiopathic PD and HC, we found an area under the ROC curve (AUC) of 0.736 (95% CI: 0.677 to 0.794) for Parkin (Figure 1D), indicating Parkin is a moderately suitable diagnosis marker for PD. The gene discussed is PRKN; the disease is Parkinson disease.