The results showed that serum A20 level was positively associated with drinking (r=0.113, P=0.039), Hb (r=0.133, P=0.015), AST (r=0.149, P=0.006), Cr (r=0.208, P<0.001), HDL (r=0.111, P=0.043) and was negatively associated with T2DM (r=-0.418, P<0.001), waist circumference (r=-0.123,P=0.038), WHR (r=-0.173,P=0.003), FPG (r=-0.396, P<0.001) and HbA1c (r=-0.205, P=0.001). Here, TNFAIP3 is linked to type 2 diabetes mellitus.