Contrary to the study's hypothesis, fasting serum insulin [PBND = −0.0 mU/L(−0.8 to 0.8), MCRD = −1.3 mU/L (−2.4 to −0.3), p = 0.034] and insulin resistance [PBND = 0.03 (−0.24–0.18), MCRD = −0.37 (−0.68 to −0.06), p = 0.030] were improved significantly in the MCRD group. The gene discussed is INS; the disease is Insulin resistance.