Verification in the AF dataset GSE14975 found that RSAD2 (AUC = 1.000, 95%CI = 1), CXCL1 (AUC = 0.880, 95%CI = 0.626–1), LRRK2 (AUC = 0.760, 95%CI = 0.4138–1), PPBP (AUC = 0.880, 95%CI = 0.626–1), and RGS18 (AUC = 0.720, 95%CI = 0.365–1), among which RSAD2 had the highest diagnostic value for AF (Figure 6A). The gene discussed is RSAD2; the disease is atrial fibrillation.