Bromodomain-containing protein 4 (BRD4), a member of the BET family, affects cell cycle progression by activating oncogenes such as c-MYC, JUNB, CCND1 and CCNA1, thereby selectively interfering with mediating cancer cell growth and escaping apoptosis (Dawson et al., 2011; Baratta et al., 2015). This evidence concerns the gene BRD4 and cancer.