PepL, consisting of the amino acid sequence Leu-Ser-Leu-Ile-Thr-Arg-Leu, has the unique ability to bind to the interleukin-6 receptor α (IL-6Rα) that is frequently overexpressed in tumor cells (Figueiredo Neto et al., 2020). The gene discussed is IL6R; the disease is neoplasm.