Moreover, there were 8 pathways that were significantly different between the DSS and RSPQ, namely glutathione metabolism, mTOR signaling pathway, amyotrophic lateral sclerosis, pathways of neurodegeneration-multiple diseases, chagas disease, amoebiasis, arginine and proline metabolism, and arachidonic acid metabolism (Table 2). This evidence concerns the gene MTOR and amebiasis.