MOG and encephalitis: We recommend that patients with clinical manifestations of encephalitis, even if the brain MRI are normal, should undergo early testing for anti-MOG antibody if they exhibit the following characteristics: (1) persistent fever; (2) elevated peripheral blood WBC counts, while PCT and CRP are normal or slightly elevated; (3) mild elevation of CSF WBC counts, normal or mild elevated protein, and normal cerebrospinal fluid glucose; (4) ineffective antibiotics or antiviral therapy.