Therefore, we detected inflammatory factors in mice by assessing alveolar lavage fluid and peripheral blood from BLM‐induced mice with AAV‐shADAM17 or AAV‐shSC, and the results showed a significant reduction in IL‐1β, TNF‐α and IL‐6 in BLM‐induced AAV‐shADAM17 mice compared with BLM‐induced AAV‐NG mice (Figure 7A–F). This evidence concerns the gene TNF and Bloom syndrome.