PTH and Huntington disease: Patients ≥ 60 years old on protein supplementation maintained hip-BMD. Hip-BMD decreased in placebo group. Similar trend was observed for the femoral neck BMD. There was a lack of effect on patients < 60 years old. There was no effect of protein supplementation on body composition or blood markers of bone metabolism (Ca, P, and PTH) in either age group. In conclusion, the intradialytic protein supplementation attenuated the decrease in hip-BMD, a predictor of fractures, in older HD patients.