Data showed that pterostilbene treatment inhibited the conversion of high-grade prostate intraepithelial neoplasia (PIN) lesions to cancer by acting through MTA1-mediated signaling to modulate PTEN acetylation, p-Akt/Akt, AR, CyclinD1, NFκB, TGFβ and IL-1β [41]. Here, PTEN is linked to prostate intraepithelial neoplasia.