Of these, 25 CpG sites showed novel associations with lipids, including those annotated to the ATP binding cassette subfamily G member 1 locus (ABCG1, cg27243685), a gene associated with reverse cholesterol transport, which subsequently correlated with a 38% higher risk of incident CHD per every standard deviation increase in methylation [51]. This evidence concerns the gene ABCG1 and coronary artery disorder.