NRG1 and myocardial infarction: Furthermore, a large proportion of differentially methylated loci (n = 42) mapped to genes previously associated with cardiac function and CVDs in the literature, such as Dysferlin (DYSF) and Neuregulin 1 (NRG1), supporting the biological relevance and candidacy of these methylation marks as potential biomarkers for myocardial infarction [44].