These differentially methylated regulatory regions annotated to several obesity-related loci, including tyrosine-protein kinase (CSK), solute carrier organic anion transporter family member 3A1 (SLCO3A1), G protein subunit gamma 7 (GNG7), G protein subunit alpha i1 (GNAI5), lipocalin 2 (LCN2), enoyl-CoA hydratase short chain 1 (ECHS1), isocitrate dehydrogenase 2 (IDH2), and CD7 molecule (CD7). This evidence concerns the gene CD7 and obesity due to melanocortin 4 receptor deficiency.