NF-κB also plays a regulatory role in the expression of genes associated with cytokines (e.g., TNF, IL-1, IL-6, IL-8) [42], adhesion molecules (e.g., VCAM-1, ICAM-1, P- and E-selectin) and chemokines (e.g., MCP-1), all of which are implicated in the development of atherosclerosis [47]. This evidence concerns the gene NFKB1 and atherosclerosis.