IFN-gamma concentration has been correlated with severe seizures [48], MIP-1 alpha was found to be at an increased concentration in the serum of patients with intractable temporal lobe epilepsy [49], and increased TARC (a TARC/sICAM5 ratio) was detected in the plasma of focal epileptic patients [50]. The gene discussed is IFNG; the disease is temporal lobe epilepsy.