TGFβ is upregulated in several eye diseases, such as pterygium, cataract, glaucoma, proliferative vitreoretinopathy, subretinal fibrosis in neovascular age-related macular degeneration, proliferative diabetic retinopathy, and orbital fibrosis in Graves’ ophthalmopathy [86]. Here, TGFB1 is linked to CAPN5-related vitreoretinopathy.