The role of the CRP is of significance, given that it has been identified as a potential mediator of carcinogenesis and cancer progression via the activation of the FcgRs/MAPK/ERK, FcgRs/NF-kB/NLRP3, and FcgRs/IL-6/AKT/STAT3 pathways [60]. This evidence concerns the gene STAT3 and cancer.