CXCL8 exerts its action by triggering multidrug resistance genes like ABCB1 in tumor blood vessels [214], ABCB5 in mesothelioma [215], and ABCB 1 in gastric cancer [216] and increasing the expression of NF-κB-regulated antiapoptotic genes like B-cell lymphoma 2 (Bcl-2) and inhibitor of apoptosis (IAP) families [217]. This evidence concerns the gene CXCL8 and neoplasm.