PCSK9 and familial hypercholesterolemia: We did not observe any statistically significant differences between the frequency of other variants, including known pathogenic variants related to familial hypercholesterolemia (FH) as well as variants of unknown significance of FH-related genes: LDLR c.667G>A, PCSK9 c.658–36G>A, and APOB c.12382G>A.