After six months of treatment, she was negative for ANA and anti-dsDNA and positive for antibodies for antiphospholipid syndrome: APL IgG 11.95 (reference range < 10 GPL); APL IgM 62.59 (reference range < 10 MPL); ACL IgG 11.91 (reference range < 10 GLP); ACL IgM 53.70 (reference range < 7 MPL); anti-β2 GP IgM 43.68 (reference range < 8 E/mL); anti-β2 GP IgG < 8 (reference range < 8 E/mL). The gene discussed is CD40LG; the disease is antiphospholipid syndrome.