To explore the impact of DV-induced soluble molecules on an endothelial cell transcriptomic profile, we performed a meta-analysis integrating data from diverse studies using expression arrays of Human Umbilical Vein Endothelial Cells (HUVEC) exposed individually to soluble factors induced by the DV infection, including ANG2, TNF-α, and VEGF. This evidence concerns the gene TNF and infection.