The alteration sites, types, and quantities of BUB1B are further illustrated in Figure 3B. Additionally, the expression of BUB1B demonstrates a correlation with tumor mutational burden (TMB) across nine cancer types, as depicted in Figure 3C. Furthermore, we found that BUB1B expression was positively correlated with MSI in five cancers but negatively correlated in DLBC (Figure 3D). This evidence concerns the gene BUB1B and cancer.