Mainly, the rs2076295 locus is directly responsible for differential RNA expression of DSP in primary epithelial cells [11], and the low levels of DSP in the lung cause increased expression of epithelial–mesenchymal transition and extracellular matrix genes promoting pulmonary fibrosis [17], one of the major concerns arising after the recovery from COVID-19 [18]. The gene discussed is DSP; the disease is pulmonary fibrosis.