To investigate this, we studied the role of CD19 and the effect of CD19 mAbs on CXCR4 signaling in GCB-DLBCL and WM models using the SU-DHL-6 (hereafter called DHL6) and BCWM.1 cell lines, respectively. Here, CXCR4 is linked to diffuse large B-cell lymphoma.