By conducting a combined integrative and bioinformatic analysis of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) datasets, Deb and colleagues [89] discovered that NEK2 and Aurora kinase A are the most activated kinases among the five common human cancers (ovarian cancer, breast cancer, colon cancer, lung adenocarcinoma, and endometrial cancer). This evidence concerns the gene NEK2 and colonic neoplasm.