Histology showed the excised lesion to be a JGCT; tumor cells were immunostained for CKAE1/AE3 (focally in a “dot-like” juxtanuclear pattern), vimentin, inhibin, CD56, CD99, WT-1, PR, and focally for calretinin (again, any IHC was indicative of the presence or absence of these proteins) (Figure 3). The gene discussed is CALB2; the disease is neoplasm.