While direct studies on the interaction between ITGA7 and MYC in LMS are lacking, some experimental data have implied that the oncoprotein MYC is a direct repressor of ITGA7 gene transcription [179], and research in other cancer types suggests that ITGA7 or other integrins can modulate intracellular signaling pathways that may intersect with MYC’s functions [180]. Here, MYC is linked to cancer.