Meanwhile, TBK1 expression was positively correlated with immunosuppressive cell markers, such as CD37, ITGAM, FUT39, CCL33, CD4, IL-2, FOXP68, CCR10, and STAT3B, inducing HCC immunosuppression and promoting HCC progression by maintaining an inflammatory phenotype [13]. This evidence concerns the gene CD4 and hepatocellular carcinoma.