When we assayed another NSCLC cell line, H1299, for changes in the key cell cycle-related proteins after MTLN KD, we observed similar decreases in p-RB and MYC and an increase in p27Kip1, indicative of G1 arrest, as well as an increase in cyclin D1 (Figure S1). The gene discussed is CCND1; the disease is non-small cell lung carcinoma.