NFKB1 and cancer: This network comprises 18 coherent FFLs, with TFs involved in key pathways such as the PI3K-Akt signaling pathway, MAPK signaling pathway, Wnt signaling pathway, androgen receptor signaling pathway, NF-κB signaling pathway, and cell cycle regulation in cancers, stepwisely contributing to dysregulation in cell proliferation, differentiation, and survival.