Additionally, many publications have shown the potential in vivo involvement of insect AMPs in antitumour action mostly based on research conducted using a genetically modified Drosophila melanogaster model, in which tumour can be induced [89]: tumour cells in D. melanogaster activate a cellular response, releasing Tumour Necrosis Factor (TNF) from haemocytes, so TNF exposes phosphatidylserine on tumour cells’ surfaces, causing them to be targeted by cationic defensin, and this interaction leads to cancer cell death and tumour regression [89]. This evidence concerns the gene TNF and cancer.